RNA Details
Disease Name
skin fibrosis
Tissue
skin
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
q-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
MIR-155
Pathway
WNT SIGNALING PATHWAY; CATENIN BETA 1; PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
Targeting miR-155 to Treat Experimental Scleroderma
Year
2016
Function
"Our data suggest the potential of mir-155 silencing as a promising treatment for dermal fibrosis, especially in topical applications."